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Quantification of 2HG enantiomers 2HG quantification in SCD erythroblasts was performed as we previously described 24 by liquid chromatographymass spectrometry (LC-MS/MS) after derivatization using N-(p-Toluenesulfonyl)-L-phenylalanyl Chloride (TSPC) on the LC-ESI-MS/MS system

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Methods 11 , 12531260 (2014)

Recently, certain senolytic and senostatic agents, such as rapamycin, Nrf2 activators, and calorie restriction, have demonstrated effectiveness in ameliorating cellular senescence

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